Formulation Capabilities
Functional Excipients
Customized Polymer and Targeting Ligand Synthesis for High Barrier Drugs
TTY's synthesis laboratory has unique capabilities and depth of experience in biodegradable polymer and phospholipid/peptide ligand synthesis. To support formulation development, we provide:
- Customized PLA (Polylactic acid) and PLGA (Poly(lactic-co-glycolic acid)) polymers from lab scale development to GMP production:
- Specific ratio of Lactic Acid/Glycolic Acid
- Molecular weight from 5,000 to 300,000 Daltons
- End group modification
- Customized polymer conformation, such as linear and star polymers
- Batch size from gram to kilogram scale
- Our synthesis experts are devoted to phospholipid ligand synthesis and peptide covalent conjugation
- Synthesis impurity standards for in-house use
- Impurity identification and preparation of raw materials, intermediates and finished products
- Preparation of phospholipid and peptide ligands for liposomal drugs
- API Survey and pre-formulation studies
- Preparation of reference standards